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Public Health Genomics and Precision Health Knowledge Base (v9.0)
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Public Health Genomics Branch
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Precision Health Database|Search|Public Health Genomics and Precision Health Knowledge Base (PHGKB)
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Last data update: May 09, 2024
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Haemochromatosis.
Paul C Adams et al. Lancet 2023
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Exploring Prognosis, Tumor Microenvironment and Tumor Immune Infiltration in Hepatocellular Carcinoma Based on ATF/CREB Transcription Factor Family Gene-Related Model.
Honghong Shen et al. Journal of hepatocellular carcinoma 2023 10327-345
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Original Article: prevalence and factors associated with liver fibrosis among first-degree relatives of Mexican Americans with hepatocellular carcinoma.
Sharpton Suzanne et al. Alimentary pharmacology & therapeutics 2023
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A Circulating MicroRNA-375 for the Detection of Liver Cancer: A Meta-Analysis.
Kong Xiangyu et al. Genetic testing and molecular biomarkers 2022 26(12) 564-572
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Genetic modifiers of penetrance to liver endpoints in HFE hemochromatosis: associations in a large community cohort.
Pilling Luke C et al. Hepatology (Baltimore, Md.) 2022
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Risk-adapted starting age of breast cancer screening in women with a family history of ovarian or other cancers: A nationwide cohort study.
Mukama Trasias et al. Cancer 2021
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Colon cancer-specific diagnostic and prognostic biomarkers based on genome-wide abnormal DNA methylation.
Wang Yilin et al. Aging 2020 Nov 12
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Classification and mutation prediction based on histopathology H&E images in liver cancer using deep learning
M Chen et al, NPJ Precision Oncology, June 8, 2020
OGDHL Expression as a Prognostic Biomarker for Liver Cancer Patients.
Jiao Yan et al. Disease markers 2019 20199037131
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Clinical Value of lncRNA LUCAT1 Expression in Liver Cancer and its Potential Pathways.
Jiao Yan et al. Journal of gastrointestinal and liver diseases : JGLD 2019 Dec 28(4) 439-447
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Deep Learning-Based Multi-Omics Integration Robustly Predicts Survival in Liver Cancer.
Chaudhary Kumardeep et al. Clinical cancer research : an official journal of the American Association for Cancer Research 2018 24(6) 1248-1259
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Opportunities in Cancer Research: The Immune System and Microbiome
NCI 2021 annual plan, 2019
The applications of metabolomics in the molecular diagnostics of cancer.
Cheung Pro Kit et al. Expert review of molecular diagnostics 2019 Aug
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FDA Approvals Provide Advances for a Range of Cancer Types
K Honey, AACR Blogs, August 6, 2019
Liver cancer: Translating '-omics' results into precision medicine for hepatocellular carcinoma.
Sia Daniela et al. Nature reviews. Gastroenterology & hepatology 2017 14(10) 571-572
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CLINGEN Actionability Report for Hemochromatosis, Type 1-HFE
ClinGen Actionability Working Group
A novel pan-cancer biomarker plasma heat shock protein 90alpha and its diagnosis determinants in clinic.
Liu Wei et al. Cancer science 2019 Jul
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The evolving landscape of precision medicine in primary liver cancer.
Martin Sean P et al. Hepatic oncology 2019 Jun 6(2) HEP12
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Recapitulation of pharmacogenomic data reveals that invalidation of SULF2 enhance sorafenib susceptibility in liver cancer.
Yoon Sarah et al. Oncogene 2018 37(32) 4443-4454
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Genomic Medicine and Implications for Hepatocellular Carcinoma Prevention and Therapy.
Dhanasekaran Renumathy et al. Gastroenterology 2019 156(2) 492-509
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Clinical significance of exosomal miRNAs and proteins in three human cancers with high mortality in China.
Li Li-Man et al. Oncology letters 2019 Jan 17(1) 11-22
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Next-generation sequencing and personalized genomic medicine in hepatobiliary malignancies.
Loaiza-Bonilla Arturo et al. Hepatic oncology 2015 Oct 2(4) 359-370
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Novel translational therapeutic strategy by sequencing primary liver cancer genomes.
Glantzounis Georgios K et al. Future oncology (London, England) 2017 13(12) 1049-1052
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Integrated genomic analysis for prediction of survival for patients with liver cancer using The Cancer Genome Atlas.
Song Yan-Zhou et al. World journal of gastroenterology 2018 Jul 24(28) 3145-3154
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Development of a Genetic and Clinical Data-Based (GC) Risk Score for Predicting Survival of Hepatocellular Carcinoma Patients After Tumor Resection.
Chen Shengsen et al. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018 Jul 48(2) 491-502
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Hereditary Hemochromatosis
CDC, July 2018
Risk of Different Cancers Among First-degree Relatives of Pancreatic Cancer Patients: Influence of Probands' Susceptibility Gene Mutation Status.
Antwi Samuel O et al. Journal of the National Cancer Institute 2018 Jul
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New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments
NCI, June 4, 2018
Association of BRAF Mutations With Survival and Recurrence in Surgically Treated Patients With Metastatic Colorectal Liver Cancer.
Margonis Georgios Antonios, et al. JAMA surgery 2018 5 0. e180996
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Annual Report to the Nation: overall cancer mortality continues to decline, prostate cancer mortality has stabilized
NCI, Press Release, May 22, 2018
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Page last reviewed:
Feb 1, 2024
Page last updated:
May 09, 2024
Content source:
Public Health Genomics Branch in the Division of Blood Disorders and Public Health Genomics
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National Center on Birth Defects and Developmental Disabilities
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